exRNAdisease

Entry Detail

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General Information

Database ID: exR0429062 RNA Name: AKAP10 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 19904302 End Site(bp): 19978343 External Links: ENSG00000108599

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TCERG1 chr5 146447311 146511961 + EFNB2 chr13 106489745 106535662 - MCFD2 chr2 46901870 46941855 - ZNF850 chr19 36714383 36772825 - ATP5MC2 chr12 53632726 53677408 - PTPRF chr1 43525187 43623666 + NSMF chr9 137447573 137459334 - GUF1 chr4 44678420 44700928 + AMPD2 chr1 109616104 109632053 + MTG2 chr20 62183029 62203568 + AASDHPPT chr11 106075501 106098699 + PROM1 chr4 15963076 16084378 - RPL27 chr17 42998273 43002959 + MICALL1 chr22 37905657 37942822 + ZNF24 chr18 35332227 35345482 - CSNK1E chr22 38290691 38318084 - ICMT chr1 6221193 6235972 - ZFAND3 chr6 37819727 38154624 + SBNO2 chr19 1107637 1174268 - OGT chrX 71533104 71575892 + FOXK2 chr17 82519713 82644662 + CANX chr5 179678628 179731641 + VMP1 chr17 59707192 59842255 + CREBL2 chr12 12611827 12645108 + GIGYF2 chr2 232697299 232860575 + TNFSF9 chr19 6531026 6535924 + SOBP chr6 107490106 107661306 + AP2A2 chr11 924894 1012245 + SLC35F2 chr11 107790991 107928293 - AP002990.1 chr11 62559603 62591531 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-454-3p chr17 59137787 59137809 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC079949.1 chr12 127142029 127146532 - AL645608.1 chr1 1011997 1013193 - TMEM147-AS1 chr19 35540738 35546029 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.