exRNAdisease

Entry Detail

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General Information

Database ID: exR0429064 RNA Name: AKAP12 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 151239967 End Site(bp): 151358559 External Links: ENSG00000131016

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MAVS chr20 3846799 3876123 + CALM1 chr14 90396502 90408268 + AP1B1 chr22 29327680 29423179 - SLC25A3 chr12 98593591 98606379 + MEPCE chr7 100428790 100434118 + PLCXD1 chrX 276322 303356 + CEP68 chr2 65056366 65087004 + ARNT chr1 150809713 150876708 - SLC3A2 chr11 62856102 62888875 + PAQR3 chr4 78887127 78939438 - RAB3GAP1 chr2 135052265 135176394 + ACTG1 chr17 81509971 81523847 - TMBIM6 chr12 49707725 49764934 + ZNF646 chr16 31074422 31084196 + PSME4 chr2 53864069 53970993 - TAF10 chr11 6606294 6612539 - LAMP1 chr13 113297239 113323672 + HNRNPF chr10 43385617 43409166 - ADGRG6 chr6 142301854 142446266 + SNX3 chr6 108211222 108261246 - GPHN chr14 66507407 67181803 + PARN chr16 14435700 14632728 - UNC45A chr15 90930180 90954093 + HERC2 chr15 28111040 28322172 - B4GALT4 chr3 119211732 119240946 - DSTN chr20 17570075 17609919 + ADGRL1 chr19 14147743 14206187 - MTHFD2 chr2 74198610 74217565 + SC5D chr11 121292681 121313410 + STT3B chr3 31532638 31637616 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC091564.7 chr11 6610883 6616594 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.