exRNAdisease

Entry Detail

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General Information

Database ID: exR0429065 RNA Name: AKAP13 RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 85380571 End Site(bp): 85749358 External Links: ENSG00000170776

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ZFAND6 chr15 80059568 80138393 + FNBP1 chr9 129887187 130043194 - IPO13 chr1 43946950 43968022 + NUDT3 chr6 34279679 34392669 - CXXC4 chr4 104468308 104494901 - RPS4X chrX 72255679 72277248 - OSTF1 chr9 75088514 75147265 + CLEC16A chr16 10944564 11182186 + HPS3 chr3 149129638 149173732 + GCSAM chr3 112120839 112133270 - CAPN1 chr11 65180566 65212006 + RBM3 chrX 48574449 48581162 + GOLGA8B chr15 34525207 34588503 - HAUS5 chr19 35612735 35625355 + CENPA chr2 26764289 26801067 + CTDNEP1 chr17 7243591 7252491 - RBM47 chr4 40423267 40630875 - PTEN chr10 87863625 87971930 + ZNF277 chr7 112206695 112343934 + SLC17A9 chr20 62952707 62969585 + SNTB2 chr16 69187129 69309052 + CGGBP1 chr3 88051944 88149885 - ARIH1 chr15 72474330 72602987 + ST6GALNAC6 chr9 127885321 127905408 - ATP5PF chr21 25716503 25735673 - PSMG1 chr21 39174769 39183488 - PCYT2 chr17 81900965 81911464 - CHD3 chr17 7884796 7912760 + ZNF354B chr5 178859953 178888122 + TMCC2 chr1 205227946 205285632 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-449a chr5 55170586 55170607 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011603.2 chr12 49090208 49093312 + AC016590.2 chr19 37337236 37337743 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL157935.2 chr9 127934503 127940952 + AL355075.4 chr14 20343048 20343685 - LINC01783 chr1 16533886 16536172 - LINC02249 chr15 30195809 30217552 + TMEM99 chr17 40819106 40836270 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.