exRNAdisease

Entry Detail

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General Information

Database ID: exR0429066 RNA Name: AKAP17A RNA Type: mRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 1591604 End Site(bp): 1602520 External Links: ENSG00000197976

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand LASP1 chr17 38869859 38921770 + TKT chr3 53224712 53256052 - RPL13 chr16 89560657 89566828 + RAB11FIP3 chr16 425649 523011 + UNCX chr7 1232872 1237326 + ARFRP1 chr20 63698642 63708025 - UBA5 chr3 132654446 132678097 + FDPS chr1 155308748 155320666 + BSG chr19 571277 583493 + CSDE1 chr1 114716913 114758676 - PI4KA chr22 20707691 20859417 - FBXW5 chr9 136940435 136944738 - MAP3K15 chrX 19360056 19515261 - PGM1 chr1 63593411 63660245 + NOA1 chr4 56963350 56977606 - CDC42EP5 chr19 54465026 54473296 - HNRNPA1P48 chr16 51553436 51647132 + TOB1 chr17 50862223 50867978 - TMUB1 chr7 151081085 151083493 - GNAS chr20 58839718 58911192 + EEF2 chr19 3976056 3985463 - TMSB4X chrX 12975110 12977227 + MATR3 chr5 139273752 139331671 + SIGMAR1 chr9 34634722 34637809 - HLA-DMA chr6 32948613 32969094 - ZNF48 chr16 30378106 30400108 + STARD3NL chr7 38178222 38230671 + SNRPN chr15 24823637 24978723 + TJP2 chr9 69121264 69274615 + CLIC4 chr1 24745382 24844321 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC124068.2 chr15 89335053 89336161 + AD000090.1 chr19 35557956 35581954 + AL122017.1 chr6 81527102 81534915 - BX284668.2 chr1 16870945 16883659 + ZNF236-DT chr18 76794732 76822295 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.