exRNAdisease

Entry Detail

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General Information

Database ID: exR0429073 RNA Name: AKAP9 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 91940867 End Site(bp): 92110673 External Links: ENSG00000127914

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CCDC85C chr14 99500190 99604207 - SFRP1 chr8 41261962 41309473 - YWHAE chr17 1344275 1400222 - RBBP6 chr16 24537693 24572863 + SMARCC1 chr3 47585269 47782106 - PABPC1 chr8 100685816 100722809 - C2orf68 chr2 85605254 85612066 - FKBP4 chr12 2794970 2805423 + KDM5C chrX 53191321 53225422 - RHOA chr3 49359145 49412998 - U2AF1 chr21 43092956 43107587 - PIGQ chr16 566995 584136 + ALDOA chr16 30064164 30070457 + UBE2C chr20 45812576 45816957 + ZDHHC9 chrX 129803288 129843909 - TPT1 chr13 45333471 45341370 - CNPY3 chr6 42929192 42939294 + OXA1L chr14 22766522 22773042 + HMGA2 chr12 65824131 65966295 + UQCC2 chr6 33694293 33711727 - KMT2B chr19 35717973 35738878 + MRPL42 chr12 93467488 93516214 + RPS13 chr11 17074388 17077715 - SALL3 chr18 78980275 79002677 + AUP1 chr2 74526645 74529760 - ILF2 chr1 153661788 153671028 - CBX3 chr7 26201162 26213607 + TUBB chr6 30720352 30725426 + C12orf10 chr12 53299695 53307177 + MEX3D chr19 1554669 1568058 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand Z98883.1 chr16 568837 576257 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.