exRNAdisease

Entry Detail

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General Information

Database ID: exR0429075 RNA Name: AKIRIN1 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 38991276 End Site(bp): 39006059 External Links: ENSG00000174574

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CHIC2 chr4 54009789 54064605 - NOP10 chr15 34341713 34343177 - DDX54 chr12 113157174 113185479 - RBM39 chr20 35701347 35742312 - MCFD2 chr2 46901870 46941855 - KIAA0319L chr1 35433492 35557950 - SH2B3 chr12 111405923 111451623 + IST1 chr16 71845996 71931199 + KMT5C chr19 55339853 55348121 + CCNB1IP1 chr14 20311368 20333312 - PJA2 chr5 109334713 109409974 - DNAJB9 chr7 108569867 108574850 + RAB3B chr1 51907956 51990700 - ANKRD17 chr4 73073376 73258798 - EIF3B chr7 2354086 2380745 + PPP1CC chr12 110719680 110742939 - SLC38A1 chr12 46183063 46270017 - CTSD chr11 1752755 1764573 - EIF4H chr7 74174245 74197101 + C12orf65 chr12 123233436 123257960 + TFRC chr3 196027183 196082096 - TXNDC5 chr6 7881517 7910788 - G3BP1 chr5 151771045 151812785 + EP400 chr12 131949942 132080460 + ZFC3H1 chr12 71609472 71667725 - TKT chr3 53224712 53256052 - CKS2 chr9 89311195 89316703 + TXN chr9 110243810 110256507 - EPAS1 chr2 46293667 46386697 + ASB1 chr2 238426742 238452250 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-1321 chrX 85835832 85835849 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC138761.1 chr17 22266395 22288301 + AP001496.2 chr18 5232876 5238526 - ARSD-AS1 chrX 2904904 2906081 + LINC01783 chr1 16533886 16536172 - MAPKAPK5-AS1 chr12 111839764 111842902 - SCARNA9 chr11 93721513 93721865 + SNHG5 chr6 85650491 85678932 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.