exRNAdisease

Entry Detail

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General Information

Database ID: exR0429077 RNA Name: AKNA RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 114334156 End Site(bp): 114394405 External Links: ENSG00000106948

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TNFAIP3 chr6 137867214 137883312 + RASGRP3 chr2 33436324 33564750 + SSR4 chrX 153793516 153798499 + RPS9 chr19 54200809 54249003 + RPS19 chr19 41860255 41872925 + ATP6V1D chr14 67294371 67360265 - UBALD2 chr17 76265348 76271298 + NDUFS4 chr5 53560633 53683338 + BRMS1 chr11 66337333 66345125 - ETFB chr19 51345169 51366418 - SKP1 chr5 134148935 134177038 - RPL11 chr1 23691742 23696835 + ABCC5 chr3 183919934 184017939 - MLST8 chr16 2204248 2209453 + RPL13 chr16 89560657 89566828 + PGRMC2 chr4 128269237 128288829 - HIKESHI chr11 86302211 86345943 + EIF4B chr12 53006158 53042209 + ERI2 chr16 20780193 20900349 - BUB3 chr10 123154402 123170467 + SHC1 chr1 154962298 154974395 - GLRX3 chr10 130136391 130184521 + HLA-DRB1 chr6 32578769 32589848 - FKBP8 chr19 18531751 18544077 - ALAS1 chr3 52198086 52214327 + TUBB chr6 30720352 30725426 + ATPAF1 chr1 46632737 46673867 - HNRNPA2B1 chr7 26173057 26201529 - PYGO2 chr1 154957026 154963853 - COX7A2L chr2 42333546 42425088 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL138895.1 chr9 114396724 114398503 - LINC00882 chr3 106449775 107240671 - MIR663AHG chr20 26167817 26251546 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.