exRNAdisease

Entry Detail

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General Information

Database ID: exR0429079 RNA Name: AKR1A1 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 45550543 End Site(bp): 45570049 External Links: ENSG00000117448

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand COG8 chr16 69320140 69339667 - ATXN7L3 chr17 44191805 44200113 - HNRNPUL1 chr19 41262496 41307787 + SNRPB chr20 2461634 2470853 - ZMAT2 chr5 140698680 140706686 + MRPL10 chr17 47823272 47831541 - EPS15 chr1 51354263 51519266 - FBLN1 chr22 45502238 45601135 + EEF1G chr11 62559596 62574086 - SLC2A4RG chr20 63739776 63744050 + POU3F2 chr6 98834574 98839458 + UBAP2L chr1 154220179 154271510 + PDK1 chr2 172555373 172608669 + RNF126 chr19 647526 663233 - MTRNR2L6 chr7 142666272 142667718 + DR1 chr1 93345907 93369493 + ZNF292 chr6 87152833 87265943 + TKT chr3 53224712 53256052 - CLUH chr17 2689386 2712663 - FP565260.6 chr21 5155499 5165472 - WDR74 chr11 62832342 62841809 - SEC13 chr3 10293131 10321112 - CDKN1A chr6 36676460 36687339 + MRPL33 chr2 27771717 27988087 + RNF114 chr20 49936336 49953885 + C1orf43 chr1 154206696 154220637 - HDGF chr1 156742109 156766925 - NAA60 chr16 3443649 3486953 + CBS chr21 43053191 43076943 - RPL3 chr22 39312882 39320389 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AC069287.1 chr11 112967 125927 - AL031005.1 chr1 21266082 21267251 + AL359924.1 chr1 237862175 237928321 + LINC01641 chr1 227393554 227431035 + MALAT1 chr11 65497688 65506516 + POLR2J4 chr7 43940895 44019175 - SLX1A-SULT1A3 chr16 30193892 30204310 + SNHG1 chr11 62851984 62855953 - SNHG3 chr1 28505980 28510892 + ZNF528-AS1 chr19 52388842 52397783 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.