exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429080 RNA Name: AKR1B1 RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 134442356 End Site(bp): 134459284 External Links: ENSG00000085662

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TUBB chr6 30720352 30725426 + PKM chr15 72199029 72231822 - INPP5F chr10 119726042 119829147 + P4HB chr17 81843161 81860624 - RPL3 chr22 39312882 39320389 - CKB chr14 103519667 103522833 - SLC12A4 chr16 67943474 67969601 - CCNB1IP1 chr14 20311368 20333312 - RPL26 chr17 8377516 8383213 - ARHGDIB chr12 14942031 14961728 - EDARADD chr1 236348257 236502915 + KLHDC3 chr6 43014103 43021298 + STK4 chr20 44966479 45080021 + TRIR chr19 12730640 12734684 - PTGIS chr20 49503874 49568137 - C12orf49 chr12 116710171 116738070 - TOMM7 chr7 22812628 22822852 - FSCN3 chr7 127591409 127602144 + CFL1 chr11 65823022 65862026 - ATP5ME chr4 672436 674330 - YWHAH chr22 31944522 31957603 + ZNF516 chr18 76357682 76495242 - GDF1 chr19 18868545 18896158 - FLRT3 chr20 14322985 14337614 - AKR1A1 chr1 45550543 45570049 + ACTB chr7 5527148 5563784 - RPL36 chr19 5674947 5691875 + PTPA chr9 129110950 129148946 + HOXB1 chr17 48528526 48531011 - ZNF277 chr7 112206695 112343934 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC135178.2 chr17 8318088 8318712 - NORAD chr20 36045618 36051018 - POLR2J4 chr7 43940895 44019175 - SNHG12 chr1 28578538 28583132 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.