exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429088 RNA Name: AKT1S1 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 49869033 End Site(bp): 49878459 External Links: ENSG00000204673

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand YIPF3 chr6 43511832 43516985 - FOXRED2 chr22 36487190 36507101 - FAM86C1 chr11 71787510 71801237 + BABAM2 chr2 27889941 28338901 + PABPN1 chr14 23321289 23326185 + BBS10 chr12 76344474 76348415 - ESYT1 chr12 56118250 56144671 + ZNF585A chr19 37106734 37172741 - SEC62 chr3 169966635 169998373 + EEF1G chr11 62559596 62574086 - SEPHS1 chr10 13317428 13348298 - STAG3 chr7 100177563 100221488 + CBX1 chr17 48070052 48101478 - KIAA2013 chr1 11919591 11926428 - IRF2BP2 chr1 234604269 234609525 - NOMO3 chr16 16232528 16294811 + KAT7 chr17 49788681 49835026 + ZFP36L1 chr14 68787660 68796253 - PODXL chr7 131500262 131558217 - CRABP2 chr1 156699606 156705816 - PILRB chr7 100352176 100367733 + AGO2 chr8 140520156 140635633 - DPY19L1 chr7 34928876 35038271 - ATF5 chr19 49928702 49933935 + ID1 chr20 31605283 31606515 + MYL6 chr12 56158161 56163496 + TMEM256-PLSCR3 chr17 7389734 7404097 - SLC6A6 chr3 14402576 14489349 + NLRX1 chr11 119166568 119184016 + HNRNPUL1 chr19 41262496 41307787 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC113189.2 chr17 7420103 7444081 + AC113189.4 chr17 7439506 7445966 + AC079949.1 chr12 127142029 127146532 - AP001626.1 chr21 42648271 42651244 - HCG18 chr6 30286690 30327382 - SLX1A-SULT1A3 chr16 30193892 30204310 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.