exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429091 RNA Name: AKTIP RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 53491040 End Site(bp): 53504411 External Links: ENSG00000166971

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AHCYL1 chr1 109984765 110023742 + AP002990.1 chr11 62559603 62591531 - ATXN2L chr16 28823035 28837237 + EEF1G chr11 62559596 62574086 - EI24 chr11 125569280 125584684 + EIF3H chr8 116642130 116766925 - ERG28 chr14 75649791 75660876 - FGF2 chr4 122826708 122898236 + FLRT3 chr20 14322985 14337614 - FRAS1 chr4 78057323 78544269 + HILPDA chr7 128455849 128458418 + HMGN3 chr6 79201245 79234738 - MT-CO3 chrMT 9207 9990 + NAPG chr18 10525905 10552764 + PIGX chr3 196639775 196736007 + PPP4R3B chr2 55547292 55618880 - PTGES3 chr12 56663341 56688408 - SH3KBP1 chrX 19533977 19887600 - SLC7A5 chr16 87830023 87869507 - TMCO3 chr13 113491021 113554590 + TMX1 chr14 51240162 51257655 + TRIM71 chr3 32817997 32897824 + TSPAN6 chrX 100627108 100639991 - TUFM chr16 28842411 28846348 - UQCR10 chr22 29767369 29770413 + VCPIP1 chr8 66628487 66667231 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.