exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429097 RNA Name: AL121845.3 RNA Type: mRNA Chromosome: chr20 Starnd: + Coordinate: Start Site(bp): 63708864 End Site(bp): 63739103 External Links: ENSG00000273154

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PPP5C chr19 46347087 46392981 + NDUFA9 chr12 4649095 4694317 + HS6ST3 chr13 96090839 96839562 + PCDH7 chr4 30720415 31146805 + RAC1 chr7 6374527 6403967 + MFSD12 chr19 3538261 3574290 - TMEM209 chr7 130164713 130207770 - HGS chr17 81683326 81703138 + GNAI1 chr7 79768028 80226181 + NSD3 chr8 38269704 38382272 - FGFR1 chr8 38400215 38468834 - TICRR chr15 89575469 89631056 + EDC4 chr16 67873052 67884499 + AC005832.4 chr12 4604944 4662643 + YIF1A chr11 66284580 66289145 - CKB chr14 103519667 103522833 - DNMT1 chr19 10133345 10231286 - COX6A1 chr12 120438090 120440737 + ZGPAT chr20 63707465 63736142 + ARFGEF1 chr8 67173511 67343781 - C6orf89 chr6 36871870 36928964 + RPN2 chr20 37178410 37241619 + SLC1A5 chr19 46774883 46788594 - POU3F2 chr6 98834574 98839458 + KMT2D chr12 49018975 49059774 - SNRPB chr20 2461634 2470853 - EFS chr14 23356403 23365752 - APIP chr11 34853094 34916379 - ISCA1 chr9 86264546 86283102 - RPS17 chr15 82536750 82540459 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012531.2 chr12 54017110 54035361 + AC109460.3 chr16 28974804 28990775 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AC005833.2 chr12 4804499 4830747 - LINC01224 chr19 23399233 23416075 - LINC02054 chr3 184399790 184457891 + NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Z84723.1 chr16 17514 35195 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.