exRNAdisease

Entry Detail

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General Information

Database ID: exR0429098 RNA Name: AL136295.5 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 24147548 End Site(bp): 24166452 External Links: ENSG00000259529

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PFN1 chr17 4945652 4949061 - THOP1 chr19 2785503 2815807 + SERBP1 chr1 67407810 67430415 - RPL30 chr8 98024851 98046469 - IRF9 chr14 24161265 24166565 + GADD45B chr19 2476122 2478259 + STAU1 chr20 49113339 49188367 - RNF31 chr14 24146683 24160660 + ACTR1B chr2 97655939 97664044 - LDHA chr11 18394560 18408425 + UQCRQ chr5 132866630 132868847 + MTRNR2L1 chr17 22523111 22524663 + B3GALT6 chr1 1232237 1235041 + SLC39A1 chr1 153959099 153968184 - PHAX chr5 126600925 126627252 + PRDX6 chr1 173477330 173488815 + HNRNPDL chr4 82422564 82430408 - SFPQ chr1 35176378 35193145 - NCL chr2 231453531 231483641 - UBA52 chr19 18571730 18577550 + JAG2 chr14 105140982 105168824 - ADCY5 chr3 123282296 123449758 - HLA-C chr6 31268749 31272130 - PRRC2A chr6 31620715 31637771 + CAPN1 chr11 65180566 65212006 + PNRC1 chr6 89080751 89085160 + NBEA chr13 34942287 35673022 + RHBDD3 chr22 29259872 29268209 - SINHCAF chr12 31280584 31327058 - CNOT4 chr7 135361795 135510127 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302c-3p chr4 112648366 112648388 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC00205 chr21 45288050 45297806 + OIP5-AS1 chr15 41283990 41309737 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.