exRNAdisease

Entry Detail

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General Information

Database ID: exR0429101 RNA Name: AL139353.1 RNA Type: mRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 31334312 End Site(bp): 31457441 External Links: ENSG00000203546

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AP002990.1 chr11 62559603 62591531 - BBS5 chr2 169479480 169506655 + BSG chr19 571277 583493 + DNAJA3 chr16 4425805 4456775 + DTD2 chr14 31446036 31457506 - EEF1G chr11 62559596 62574086 - EIF3L chr22 37848868 37889407 + HEATR5A chr14 31291788 31420550 - IRS4 chrX 108732482 108736409 - LCAT chr16 67939750 67944131 - LDHA chr11 18394560 18408425 + LSM4 chr19 18306230 18323274 - NAP1L1 chr12 76036585 76084958 - PMPCA chr9 136410641 136423761 + PTPRF chr1 43525187 43623666 + RPL13 chr16 89560657 89566828 + RPS29 chr14 49570984 49599164 - SUPT5H chr19 39436156 39476670 + TMBIM6 chr12 49707725 49764934 + TNFRSF14 chr1 2555639 2565382 + UFM1 chr13 38349849 38363619 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.