exRNAdisease

Entry Detail

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General Information

Database ID: exR0429109 RNA Name: ALAD RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 113386312 End Site(bp): 113401290 External Links: ENSG00000148218

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SUSD2 chr22 24181487 24189106 + EIF4G2 chr11 10797050 10808940 - RTL6 chr22 44492583 44498233 - FAM32A chr19 16185380 16192046 + PKM chr15 72199029 72231822 - MRPL12 chr17 81703367 81707517 + NEK1 chr4 169392857 169612629 - NAPB chr20 23374519 23421519 - TAF6L chr11 62771357 62787342 + GAPDH chr12 6534512 6538374 + UBR5 chr8 102252273 102412759 - CHD4 chr12 6570082 6614524 - TIPIN chr15 66336191 66386746 - ZCCHC8 chr12 122471599 122501073 - HNRNPK chr9 83968083 83980616 - AC139530.2 chr17 81703371 81720539 + ARHGDIA chr17 81867721 81871378 - RPL4 chr15 66498015 66524532 - PFN1 chr17 4945652 4949061 - HLA-DRA chr6 32439878 32445046 + POU5F1 chr6 31164337 31180731 - YBX3 chr12 10699089 10723323 - RAB13 chr1 153981617 153986358 - RPL41 chr12 56116590 56117967 + HSPBP1 chr19 55262223 55280381 - PLEC chr8 143915147 143976734 - HELLS chr10 94501434 94613905 + PRC1 chr15 90966040 90995629 - CRMP1 chr4 5748084 5893086 - C17orf100 chr17 6651762 6693202 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC068831.7 chr15 91022766 91023200 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.