exRNAdisease

Entry Detail

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General Information

Database ID: exR0429110 RNA Name: ALAS1 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 52198086 End Site(bp): 52214327 External Links: ENSG00000023330

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RAB28 chr4 13361354 13484365 - SUPT6H chr17 28662198 28702679 + ENTPD1 chr10 95711779 95877266 + SELENOH chr11 57741250 57743554 + RBM15B chr3 51391285 51397908 + AGO4 chr1 35808016 35857890 + STIP1 chr11 64185272 64204543 + RAB11B chr19 8389981 8404434 + RBP1 chr3 139517434 139539829 - ATP5MG chr11 118401606 118431496 + RPS29 chr14 49570984 49599164 - MRPL4 chr19 10251901 10260055 + AP2S1 chr19 46838136 46850992 - RPL7 chr8 73290242 73295789 - RPL23 chr17 38847860 38853764 - NR3C1 chr5 143277931 143435512 - ABLIM1 chr10 114431113 114768061 - ENO1 chr1 8861000 8879190 - RPL37A chr2 216498825 216579180 + RAB1A chr2 65070696 65130331 - MGST1 chr12 16347142 16609259 + CBX1 chr17 48070052 48101478 - MYL6 chr12 56158161 56163496 + HNRNPA0 chr5 137745651 137754363 - ZNF207 chr17 32350117 32381886 + PPFIBP2 chr11 7513298 7657127 + KLHL23 chr2 169694488 169776989 + PARVB chr22 43999211 44172949 + ARHGEF11 chr1 156934840 157045370 - NDFIP2 chr13 79481124 79556075 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.