exRNAdisease

Entry Detail

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General Information

Database ID: exR0429113 RNA Name: ALCAM RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 105366909 End Site(bp): 105576900 External Links: ENSG00000170017

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ZNF525 chr19 53365693 53392217 + RPL34 chr4 108620566 108630412 + EIF5A chr17 7306999 7312463 + OAZ1 chr19 2269509 2273490 + MT-CO1 chrMT 5904 7445 + SLC10A7 chr4 146253975 146521964 - FBXO45 chr3 196568611 196589059 + ZNF664 chr12 123971845 124015439 + EIF3F chr11 7970251 8001862 + NUDT5 chr10 12165330 12196144 - NOP56 chr20 2652593 2658393 + CMTM6 chr3 32481312 32502852 - POLR2E chr19 1086574 1095380 - FRAS1 chr4 78057323 78544269 + VAMP3 chr1 7771296 7781432 + ATP5MG chr11 118401606 118431496 + FKBP8 chr19 18531751 18544077 - TMEM107 chr17 8172457 8176399 - ADK chr10 74151202 74709963 + CYTIP chr2 157414619 157488961 - CDH3 chr16 68636189 68722616 + KBTBD2 chr7 32868172 32894131 - EIF3E chr8 108201216 108435333 - RPLP0 chr12 120196699 120201235 - PRRC2B chr9 131373636 131500197 + RBM5 chr3 50088919 50119021 + PPME1 chr11 74171267 74254703 + BTG1 chr12 92140278 92145846 - IGFBP2 chr2 216632828 216664436 + SPRED1 chr15 38252836 38357249 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC024940.6 chr12 31280422 31280895 - AD000090.1 chr19 35557956 35581954 + LINC00992 chr5 117415509 117546298 + MALAT1 chr11 65497688 65506516 + PRNCR1 chr8 127079874 127092600 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.