exRNAdisease

Entry Detail

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General Information

Database ID: exR0429114 RNA Name: ALDH16A1 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 49453225 End Site(bp): 49471050 External Links: ENSG00000161618

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MED22 chr9 133338312 133348131 - SOX4 chr6 21593751 21598619 + SLC52A2 chr8 144354135 144361272 + LARGE2 chr11 45921621 45929096 + EEF1A1 chr6 73515750 73523797 - FASTK chr7 151076593 151080866 - FAT1 chr4 186587794 186726722 - LGALS9 chr17 27629798 27649560 + PPP1R10 chr6 30600413 30618612 - GRB10 chr7 50590063 50793462 - ATP6V1G2-DDX39B chr6 31530219 31546608 - SLC25A11 chr17 4937130 4940053 - GSPT1 chr16 11868128 11916082 - HOXB3 chr17 48548870 48604912 - THOP1 chr19 2785503 2815807 + CYB5B chr16 69424619 69466264 + ARFGAP1 chr20 63272785 63289790 + CBX6 chr22 38861422 38872249 - CTNNA1 chr5 138610967 138935034 + B3GALT6 chr1 1232237 1235041 + ADAMTS1 chr21 26835755 26845409 - DHX36 chr3 154272546 154324487 - ISG20L2 chr1 156721891 156728799 - CDC34 chr19 531760 542092 + ZNRF2 chr7 30284597 30367689 + BCR chr22 23179704 23318037 + EEF2 chr19 3976056 3985463 - RBM15 chr1 110338506 110346681 + GPATCH2L chr14 76151916 76254342 + DDX39B chr6 31530219 31542448 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020928.2 chr19 36773712 36775908 - AC067852.1 chr17 42536510 42562062 + AC132217.1 chr11 2129121 2129964 - VPS9D1-AS1 chr16 89711856 89718165 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.