exRNAdisease

Entry Detail

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General Information

Database ID: exR0429115 RNA Name: ALDH18A1 RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 95605941 End Site(bp): 95656711 External Links: ENSG00000059573

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand GTF3C2 chr2 27325849 27357034 - MCM7 chr7 100092728 100101940 - GABARAP chr17 7240008 7242449 - PTPRS chr19 5158495 5340803 - OPTN chr10 13099449 13138308 + HOXD3 chr2 176136612 176173102 + ELL2 chr5 95885098 95961851 - MTA2 chr11 62593214 62601865 - HNRNPC chr14 21209136 21269494 - CCNF chr16 2429394 2458854 + PGAM1 chr10 97426191 97433444 + HMGXB3 chr5 150000046 150053142 + ARPC1B chr7 99374249 99394816 + HSPA5 chr9 125234853 125241343 - CSDE1 chr1 114716913 114758676 - MTG1 chr10 133394094 133422520 + SRM chr1 11054584 11060020 - AKAP13 chr15 85380571 85749358 + MRFAP1 chr4 6640091 6642745 + E2F4 chr16 67192155 67198918 + EEF2KMT chr16 5084284 5097795 - SCAMP2 chr15 74843730 74873365 - LASP1 chr17 38869859 38921770 + AHCY chr20 34280268 34311802 - ACAT2 chr6 159762045 159779112 + TNC chr9 115019575 115118257 - CAMTA2 chr17 4967992 4987675 - CIAO1 chr2 96266159 96274173 + DDX24 chr14 94048287 94081212 - SRRM2 chr16 2752626 2772538 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010319.3 chr19 17419305 17419774 - AC016876.2 chr17 7581964 7584086 - AL031595.3 chr22 44139365 44153626 + FOXD2-AS1 chr1 47432133 47434641 - LINC00667 chr18 5237826 5290608 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.