exRNAdisease

Entry Detail

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General Information

Database ID: exR0429119 RNA Name: ALDH1B1 RNA Type: mRNA Chromosome: chr9 Starnd: + Coordinate: Start Site(bp): 38392702 End Site(bp): 38398661 External Links: ENSG00000137124

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand UPF1 chr19 18831938 18868236 + ISG20L2 chr1 156721891 156728799 - STAU1 chr20 49113339 49188367 - SNURF chr15 24954986 24977850 + P4HB chr17 81843161 81860624 - GLYR1 chr16 4803203 4847288 - POLRMT chr19 617221 633537 - C9orf129 chr9 93318199 93346414 - LSP1 chr11 1852970 1892267 + HNRNPU chr1 244840638 244864560 - TPCN1 chr12 113221050 113298585 + LRG1 chr19 4536402 4540036 - RNF150 chr4 140859807 141212877 - CLDN6 chr16 3014712 3020071 - TXNDC5 chr6 7881517 7910788 - SSBP1 chr7 141738334 141787922 + PPP1R12A chr12 79773563 79935460 - YIPF1 chr1 53851719 53889798 - BLOC1S5-TXNDC5 chr6 7881522 8064364 - WDR70 chr5 37379285 37753435 + SPOP chr17 49598884 49678163 - TP53 chr17 7661779 7687550 - SNRPN chr15 24823637 24978723 + NOLC1 chr10 102152176 102163871 + TMEM132B chr12 125186836 125662377 + HMGA1 chr6 34236873 34246231 + LY75 chr2 159803355 159904756 - PTP4A1 chr6 63521746 63583436 + HSP90AB1 chr6 44246166 44253888 + KLC2 chr11 66257294 66267860 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020663.1 chr16 4730115 4752565 - AP003175.1 chr11 75069243 75096964 - SNHG3 chr1 28505980 28510892 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.