exRNAdisease

Entry Detail

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General Information

Database ID: exR0429122 RNA Name: ALDH2 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 111766887 End Site(bp): 111817532 External Links: ENSG00000111275

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand WASF3 chr13 26557683 26688948 + RACK1 chr5 181236897 181248096 - ANKS1A chr6 34889255 35091406 + NME2 chr17 51165435 51171747 + EIF5A chr17 7306999 7312463 + ZNF891 chr12 133106817 133130473 - NPM1 chr5 171387116 171411137 + LYSMD1 chr1 151159748 151165948 - PEX5 chr12 7188685 7218574 + RBM39 chr20 35701347 35742312 - LAMA5 chr20 62307955 62367312 - PITPNM1 chr11 67491768 67506263 - RPL28 chr19 55385345 55403250 + ANKRD11 chr16 89267630 89490561 - TUBA1C chr12 49188736 49274603 + RBPJ chr4 26163455 26435131 + PRPF19 chr11 60890547 60906585 - PRTG chr15 55611544 55743152 - ZNF671 chr19 57719751 57727624 - CSK chr15 74782057 74803198 + AC002996.1 chr12 111753890 111791418 + GPT2 chr16 46884362 46931289 + PTPN9 chr15 75463251 75579315 - SIRT7 chr17 81911939 81921323 - DR1 chr1 93345907 93369493 + ACTB chr7 5527148 5563784 - AC010422.3 chr19 12643831 12648397 - RPL13 chr16 89560657 89566828 + APOBEC3G chr22 39077067 39087743 + SIKE1 chr1 114769479 114780685 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC092117.1 chr16 2777319 2780568 + AC108134.2 chr16 3156736 3157483 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.