exRNAdisease

Entry Detail

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General Information

Database ID: exR0429127 RNA Name: ALDH6A1 RNA Type: mRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 74056847 End Site(bp): 74084492 External Links: ENSG00000119711

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SYNCRIP chr6 85607785 85643792 - SRPRB chr3 133784023 133825772 + HNRNPA1L2 chr13 52642425 52643796 + SLC12A2 chr5 128083766 128189677 + KIAA0556 chr16 27550133 27780369 + RPL8 chr8 144789765 144792587 - ATP5PB chr1 111448864 111462773 + CFL1 chr11 65823022 65862026 - NOP53 chr19 47745546 47757058 + SFRP2 chr4 153780591 153789083 - METAP1 chr4 98995659 99062809 + PPP1R37 chr19 45091396 45148077 + DNAJA2 chr16 46955362 46973674 - ZNF544 chr19 58228594 58277495 + COLGALT1 chr19 17555649 17583162 + SRSF1 chr17 58000919 58007346 - BRD2 chr6 32968594 32981505 + EIF1 chr17 41688885 41692668 + BOD1 chr5 173607145 173616659 - BCL2L13 chr22 17628855 17730855 + COPS4 chr4 83034447 83075818 + TSPAN3 chr15 77041404 77083984 - CCND1 chr11 69641156 69654474 + LIN28A chr1 26410817 26429728 + PTPRU chr1 29236516 29326813 + CALM3 chr19 46601074 46610782 + AC015813.2 chr17 57989038 58007246 - RACK1 chr5 181236897 181248096 - PRPSAP2 chr17 18840085 18931287 + HSP90AB1 chr6 44246166 44253888 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand PSMA3-AS1 chr14 58265365 58298134 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.