exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429128 RNA Name: ALDH7A1 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 126531200 End Site(bp): 126595362 External Links: ENSG00000164904

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CNDP2 chr18 74495816 74523454 + SLC2A3 chr12 7919230 7936187 - CRISPLD1 chr8 74984505 75034558 + NUCKS1 chr1 205712822 205750182 - LIN28B chr6 104936616 105083332 + HERC2 chr15 28111040 28322172 - CALCOCO1 chr12 53708517 53727745 - DUSP16 chr12 12473282 12562863 - NASP chr1 45583846 45618904 + WDR24 chr16 684622 690444 - SBNO1 chr12 123289109 123364847 - CIB2 chr15 78104606 78131535 - EEF2 chr19 3976056 3985463 - SF3B1 chr2 197388515 197435091 - CAPZA1 chr1 112619805 112671616 + KHDRBS1 chr1 32013868 32060850 + TUBA1C chr12 49188736 49274603 + SOX13 chr1 204073115 204127743 + EIF3C chr16 28688558 28735730 + ERLIN2 chr8 37736601 37758422 + CD276 chr15 73683966 73714514 + DDHD2 chr8 38225218 38275558 + CYTL1 chr4 5014586 5019458 - WDHD1 chr14 54938949 55027105 - EIF4H chr7 74174245 74197101 + KANSL3 chr2 96593170 96642787 - SCRN1 chr7 29920104 29990289 - DPPA4 chr3 109326141 109337572 - ZNF589 chr3 48241100 48299253 + RPL23 chr17 38847860 38853764 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012467.2 chr3 53858994 53861576 - AC016876.2 chr17 7581964 7584086 - SNHG14 chr15 24978583 25420336 + SOX21-AS1 chr13 94703454 94803430 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.