exRNAdisease

Entry Detail

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General Information

Database ID: exR0429130 RNA Name: ALDH9A1 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 165662216 End Site(bp): 165698863 External Links: ENSG00000143149

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FYN chr6 111660332 111873452 - NIPSNAP1 chr22 29554808 29581327 - GSE1 chr16 85169525 85676204 + KCNMB4 chr12 70366290 70434292 + RPS15 chr19 1438358 1440494 + HES1 chr3 194136148 194138732 + B4GALT6 chr18 31622247 31685836 - FBRSL1 chr12 132489551 132585188 + TCF19 chr6 31158547 31167159 + RABEP2 chr16 28904421 28936526 - MORF4L2 chrX 103675496 103688158 - PCK2 chr14 24094053 24110598 + LRRFIP1 chr2 237627587 237813682 + SRSF2 chr17 76734115 76737374 - ITCH chr20 34363241 34540748 + ZNF384 chr12 6666477 6689572 - SPARC chr5 151661096 151686975 - CD55 chr1 207321376 207386804 + ENO1 chr1 8861000 8879190 - RPS6 chr9 19375715 19380236 - DDOST chr1 20651767 20661544 - SRSF3 chr6 36594353 36605600 + KHSRP chr19 6413348 6424794 - RALY chr20 33993646 34108308 + SLC4A8 chr12 51391317 51515763 + MRRF chr9 122264603 122331337 + MCM7 chr7 100092728 100101940 - DVL3 chr3 184155377 184173614 + GJA1 chr6 121435595 121449727 + MTA1 chr14 105419820 105470729 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-1270 chr19 20399320 20399342 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026740.1 chr5 675826 676616 + AL139819.1 chr10 100335563 100346390 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.