exRNAdisease

General Information

Database ID:

exR0429131

RNA Name:

ALDOA

RNA Type:

mRNA

Chromosome:

chr16

Starnd:

Coordinate:

Start Site(bp):

30064164

End Site(bp):

30070457

External Links:

Disease Information

Disease Name:	Pediatric TB meningitis
Disease Category:	Infections
MeSH ID:	D014390
Type:	Diseases Category/Infections
Alias:	Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID:	GSE122377
Description:	Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:	Disease Sample Source
Case Disease Type:	Pediatric TB meningitis
Case Disease SubType:	NA
Case Sample:	Pediatric TB meningitis
Control Sample:	Lumbar Puncture Cerebrospinal Fluid
Number of Case:	12
Number of Control:	12
Number of Samples:	24

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC104452.1	chr3	49416777	49429314	-
AL590764.2	chrX	71103987	71111575	-
AKAP8L	chr19	15380050	15419141	-
AC007192.1	chr19	18153158	18178117	+
ADSL	chr22	40346500	40390463	+
AC092143.1	chr16	89919165	89936092	+
ACLY	chr17	41866917	41930542	-
ACTN4	chr19	38647649	38731589	+
AKAP8	chr19	15353385	15379798	-
AKIRIN1	chr1	38991276	39006059	+
ACTA1	chr1	229431245	229434098	-
AL365205.1	chr6	41780349	41790141	+
AFG3L2	chr18	12328944	12377227	-
AL136454.1	chr1	192716132	192716653	+
AHDC1	chr1	27534035	27604431	-
AHCYL1	chr1	109984765	110023742	+
ADCY1	chr7	45574140	45723116	+
AHRR	chr5	271670	438291	+
AL117348.2	chr1	225886696	225924278	-
AL109827.1	chr20	35632340	35674544	-
AC010132.3	chr7	42909273	42932174	-
ACTG1	chr17	81509971	81523847	-
AC008763.3	chr19	7678501	7682854	+
AHSA1	chr14	77457870	77469472	+
AC040162.1	chr16	67929614	67936017	-
AC011448.1	chr19	19516227	19536076	+
ACP1	chr2	264140	278283	+
AC131160.1	chr3	183815568	183884889	-
AC245033.1	chr15	82536788	82573194	-
AC010422.3	chr19	12643831	12648397	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-122-5p	chr18	58451088	58451109	+
hsa-miR-146a-5p	chr5	160485372	160485393	+
hsa-miR-302b-3p	chr4	112648489	112648511	-
hsa-miR-574-5p	chr4	38868056	38868078	+
hsa-miR-3654	chr7	133034860	133034878	-

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC007952.4	chr17	19112000	19112636	-
AC016747.4	chr2	61115787	61164825	+
AC016876.2	chr17	7581964	7584086	-
AC023509.1	chr12	53441741	53467528	+
AC079781.5	chr7	97851688	97972985	-
AC091564.7	chr11	6610883	6616594	-
AC114271.1	chr19	10333436	10336248	+
AC244090.1	chrX	154424380	154428479	-
AD000090.1	chr19	35557956	35581954	+
AL117378.1	chr6	131901963	131920565	+
AC005632.3	chr16	21626742	21627569	+
AC239799.1	chr1	146235806	146237807	+
AL031005.1	chr1	21266082	21267251	+
AL355075.4	chr14	20343048	20343685	-
AL391422.3	chr6	3831933	3855737	+
AP005263.1	chr18	9102736	9254346	+
DANCR	chr4	52712404	52720351	+
MIR3142HG	chr5	160438594	160487426	+
MIR762HG	chr16	30875222	30895220	+
SNHG5	chr6	85650491	85678932	-
SNHG8	chr4	118278709	118285316	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	31434901
Title:	Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:	Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:	Nat Commun. 2019 Aug 21;10(1):3767.
Description:	Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.