exRNAdisease

Entry Detail

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General Information

Database ID: exR0429334 RNA Name: AP002990.1 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 62559603 End Site(bp): 62591531 External Links: ENSG00000255508

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACIN1 chr14 23058564 23095614 - AC245033.1 chr15 82536788 82573194 - AKAP10 chr17 19904302 19978343 - AL049629.2 chr11 33698261 33722467 - AC005258.1 chr19 2269525 2341172 + AC098484.3 chr1 42767292 42794493 + AC012254.2 chr18 47108188 47176345 - AC138811.2 chr16 18788063 18801519 - ACVR2B chr3 38453890 38493142 + AL513165.2 chr9 37512547 37592469 - AL139353.1 chr14 31334312 31457441 - ACD chr16 67657512 67660815 - ACADS chr12 120725774 120740008 + ACTG1 chr17 81509971 81523847 - ACO2 chr22 41469117 41528989 + AL136295.4 chr14 24180395 24190416 - AC020922.1 chr19 55352301 55359516 - ACAD8 chr11 134253495 134265855 + AC008763.3 chr19 7678501 7682854 + AC073508.2 chr17 40627356 40665141 - AK2 chr1 33007940 33080996 - AL162417.1 chr9 133098121 133163914 - AKT2 chr19 40230317 40285536 - ADAR chr1 154582057 154628013 - ACTB chr7 5527148 5563784 - ABI2 chr2 203328239 203447728 + ABHD17A chr19 1876810 1885547 - AC091167.6 chr15 90266317 90314499 + AKIRIN1 chr1 38991276 39006059 + AHSA1 chr14 77457870 77469472 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1244 chr2 231713368 231713393 + hsa-miR-3648 chr21 8987026 8987046 + hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-6747-3p chr11 62567011 62567031 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004224.2 chr16 3458071 3515564 + AC004687.1 chr17 58330884 58332508 - AC007952.4 chr17 19112000 19112636 - AC008124.1 chr12 45718046 45727775 - AC010327.5 chr19 55216660 55221616 + AC011461.1 chr19 10490339 10491000 - AC012236.1 chr15 31221999 31230838 - AC015917.2 chr17 28405240 28406796 + AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - AC021078.1 chr5 149494314 149504670 - AC022167.2 chr16 8848105 8860456 + AC091564.7 chr11 6610883 6616594 - AC107884.1 chr11 7418826 7513644 - AC107959.1 chr8 22984596 23019335 - AC113189.2 chr17 7420103 7444081 + AC113189.4 chr17 7439506 7445966 + AC132217.1 chr11 2129121 2129964 - AC139149.1 chr17 81514047 81527776 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL035458.2 chr20 34234840 34281173 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.