exRNAdisease

Entry Detail

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General Information

Database ID: exR0429437 RNA Name: ARF1 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 228082660 End Site(bp): 228099212 External Links: ENSG00000143761

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006064.6 chr12 6556886 6607367 - AC011455.2 chr19 38915404 38949855 - AC073610.2 chr12 48903503 48957365 - ACADVL chr17 7217125 7225266 + ACTA1 chr1 229431245 229434098 - ACTB chr7 5527148 5563784 - ACTN4 chr19 38647649 38731589 + ACTR10 chr14 58200080 58235636 + ACTR2 chr2 65227753 65271253 + ADGRA2 chr8 37784191 37844896 + AFDN chr6 167826922 167972023 + AGO4 chr1 35808016 35857890 + AGPAT2 chr9 136673143 136687457 - AGPAT3 chr21 43865223 43987592 + AIMP2 chr7 6009255 6023834 + AKAP8L chr19 15380050 15419141 - AKAP9 chr7 91940867 92110673 + AL713999.1 chr1 155169409 155187272 - ALDH5A1 chr6 24494867 24537207 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3610 chr8 116874740 116874759 - hsa-miR-3620-3p chr1 228097320 228097341 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AC245014.3 chr1 145281116 145281462 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.