exRNAdisease

Entry Detail

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General Information

Database ID: exR0429486 RNA Name: ARHGDIA RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 81867721 End Site(bp): 81871378 External Links: ENSG00000141522

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABI2 chr2 203328239 203447728 + AC010132.3 chr7 42909273 42932174 - AC011005.1 chr7 129126518 129130793 + AC018512.1 chr15 43772617 43799133 - AC020909.1 chr19 50415799 50428409 + AC093525.2 chr16 2496032 2520218 + AC120057.2 chr17 7240427 7244635 - ACBD6 chr1 180269653 180502954 - ACER3 chr11 76860867 77026797 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAR chr1 154582057 154628013 - ADORA2A chr22 24417879 24442357 + AGRN chr1 1020120 1056118 + AKT1 chr14 104769349 104795751 - AKT1S1 chr19 49869033 49878459 - ALAD chr9 113386312 113401290 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-339-5p chr7 1022990 1023012 - hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-588 chr6 126484646 126484666 + hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-744-5p chr17 12081909 12081930 + hsa-miR-1321 chrX 85835832 85835849 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007218.1 chr16 9666885 9676843 - AC060780.1 chr17 43148368 43171037 - AC099329.1 chr3 42785087 42852428 - AC109460.3 chr16 28974804 28990775 + AC124068.2 chr15 89335053 89336161 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.