exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429722 RNA Name: ATP1A1 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 116372668 End Site(bp): 116410261 External Links: ENSG00000163399

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004922.1 chr7 99325879 99394653 + AC005943.1 chr19 1578339 1605445 - AC007192.1 chr19 18153158 18178117 + AC008982.1 chr19 38817471 38840178 - AC012254.2 chr18 47108188 47176345 - AC027644.4 chr7 66628958 66811189 + AC105052.1 chr7 102582523 102642869 - AC110275.1 chr8 43018424 43077334 + AC120057.2 chr17 7240427 7244635 - AC139530.2 chr17 81703371 81720539 + ACKR3 chr2 236567787 236582354 + ACTC1 chr15 34790230 34795549 - ACTG1 chr17 81509971 81523847 - ADCY3 chr2 24819169 24919839 - AHDC1 chr1 27534035 27604431 - AK3 chr9 4709556 4742043 - AK9 chr6 109492856 109691217 - AKR7A2 chr1 19303965 19312146 - AL136454.1 chr1 192716132 192716653 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC051619.6 chr15 45198517 45199139 - AC067930.1 chr8 143579636 143580670 + AC129492.1 chr17 8079482 8081565 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL118558.3 chr14 101948347 101949425 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.