exRNAdisease

Entry Detail

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General Information

Database ID: exR0429741 RNA Name: ATP5F1A RNA Type: mRNA Chromosome: chr18 Starnd: - Coordinate: Start Site(bp): 46080248 End Site(bp): 46104334 External Links: ENSG00000152234

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF2 chr7 151207837 151227166 - ABHD2 chr15 89087459 89202355 + ABRAXAS2 chr10 124801819 124836667 + AC002985.1 chr19 18907013 18934397 - AC073508.2 chr17 40627356 40665141 - AC078927.1 chr12 66123917 66169985 - AC104452.1 chr3 49416777 49429314 - AC114490.2 chr1 34981533 35031741 - AC244197.3 chrX 149477104 149540926 - AC245033.1 chr15 82536788 82573194 - ACKR3 chr2 236567787 236582354 + ACLY chr17 41866917 41930542 - ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAR chr1 154582057 154628013 - ADD1 chr4 2843857 2930076 + ADNP chr20 50888916 50931437 - AFDN chr6 167826922 167972023 + AGAP3 chr7 151085831 151144436 + AGPAT5 chr8 6708642 6761503 + AHCY chr20 34280268 34311802 - AKAP1 chr17 57085092 57121346 + AKAP12 chr6 151239967 151358559 + AKR1A1 chr1 45550543 45570049 + AL590764.2 chrX 71103987 71111575 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005062.1 chr7 19918981 20140453 - AC005899.4 chr17 32328441 32329395 + AC023509.1 chr12 53441741 53467528 + AC064802.1 chr8 114282067 114295839 + AC091564.7 chr11 6610883 6616594 - AC106864.1 chr4 112693047 112706810 - AC124068.2 chr15 89335053 89336161 + AC132217.1 chr11 2129121 2129964 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.