exRNAdisease

Entry Detail

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General Information

Database ID: exR0429742 RNA Name: ATP5F1B RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 56638175 End Site(bp): 56645984 External Links: ENSG00000110955

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTN4 chr19 38647649 38731589 + AIMP1 chr4 106315544 106349456 + ADGRL2 chr1 81306160 81992436 + ACTR3 chr2 113890063 113962596 + AGL chr1 99850361 99924023 + AC120057.2 chr17 7240427 7244635 - AKAP13 chr15 85380571 85749358 + ACTN1 chr14 68874143 68979440 - AHCY chr20 34280268 34311802 - AC091167.2 chr15 90249556 90272208 + ABHD17A chr19 1876810 1885547 - ACAA2 chr18 49782164 49813953 - ACTB chr7 5527148 5563784 - AC008397.2 chr19 18207961 18255419 - ACTA2 chr10 88935074 88991339 - AL136454.1 chr1 192716132 192716653 + AL713999.1 chr1 155169409 155187272 - AC107871.1 chr15 68184032 68229718 - AC008982.1 chr19 38817471 38840178 - ABLIM1 chr10 114431113 114768061 - AKT2 chr19 40230317 40285536 - AL136295.1 chr14 24189157 24213473 - AC006064.6 chr12 6556886 6607367 - AC004922.1 chr7 99325879 99394653 + AL133352.1 chr10 100505628 100529881 - ALDOA chr16 30064164 30070457 + ACTG1 chr17 81509971 81523847 - ALDH7A1 chr5 126531200 126595362 - ADAT2 chr6 143422832 143450695 - AFAP1 chr4 7758714 7939926 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-26b-5p chr2 218402657 218402677 + hsa-miR-29a-3p chr7 130876748 130876769 - hsa-miR-1291 chr12 48654494 48654517 - hsa-miR-4485-3p chr11 10508277 10508296 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004816.1 chr14 70809841 70815994 + AC005899.4 chr17 32328441 32329395 + AC007009.1 chr7 8262233 8262821 + AC007128.1 chr7 8262264 8344516 + AC008738.7 chr19 33207129 33207639 + AC012360.3 chr2 105334027 105337475 - AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC026362.1 chr12 122975320 122982907 + AC245014.3 chr1 145281116 145281462 + AL096870.2 chr14 24209646 24215987 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.