exRNAdisease

Entry Detail

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General Information

Database ID: exR0429748 RNA Name: ATP5MC2 RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 53632726 End Site(bp): 53677408 External Links: ENSG00000135390

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCE1 chr4 145098288 145129524 + AC004922.1 chr7 99325879 99394653 + AC005258.1 chr19 2269525 2341172 + AC007192.1 chr19 18153158 18178117 + AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC023055.1 chr12 55757275 55827546 - AC118553.2 chr1 99970011 100083321 + AC124312.1 chr15 24955034 25000276 + AC138811.2 chr16 18788063 18801519 - AC245033.1 chr15 82536788 82573194 - ACAD9 chr3 128879596 128916067 + ACAT2 chr6 159762045 159779112 + ACLY chr17 41866917 41930542 - ACOT7 chr1 6264269 6394391 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADCY1 chr7 45574140 45723116 + ADH5 chr4 99070978 99088801 - AHCY chr20 34280268 34311802 - AJUBA chr14 22971177 22982551 - AKAP10 chr17 19904302 19978343 - AKAP17A chrX 1591604 1602520 + AL132780.3 chr14 22946270 22982258 - ALDH7A1 chr5 126531200 126595362 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3654 chr7 133034860 133034878 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005618.1 chr5 141326210 141329357 + AC007952.4 chr17 19112000 19112636 - AC010733.2 chr2 60925909 60931610 + AC022784.6 chr8 9158063 9158621 + AC078785.1 chr3 113019468 113184377 + AC079781.5 chr7 97851688 97972985 - AC103974.1 chr11 18706537 18740568 + AC104109.4 chr5 134205614 134371044 - AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.