exRNAdisease

Entry Detail

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General Information

Database ID: exR0429749 RNA Name: ATP5MC3 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 175176258 End Site(bp): 175184607 External Links: ENSG00000154518

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD5 chr3 43690108 43734371 + ABLIM1 chr10 114431113 114768061 - ABT1 chr6 26596953 26600739 + AC004922.1 chr7 99325879 99394653 + AC020922.1 chr19 55352301 55359516 - AC073082.1 chr2 48632291 48755724 - AC091167.2 chr15 90249556 90272208 + AC244197.3 chrX 149477104 149540926 - ACAT2 chr6 159762045 159779112 + ACOT7 chr1 6264269 6394391 - ADAM17 chr2 9488486 9556732 - ADNP chr20 50888916 50931437 - AHCY chr20 34280268 34311802 - AIMP1 chr4 106315544 106349456 + AK4 chr1 65147549 65232145 + AL021546.1 chr12 120438198 120460006 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-432-5p chr14 100884496 100884518 + hsa-miR-3652 chr12 103930425 103930442 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC099343.3 chr4 184471924 184472609 - AC108134.2 chr16 3156736 3157483 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.