exRNAdisease

Entry Detail

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General Information

Database ID: exR0429838 RNA Name: B2M RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 44711487 End Site(bp): 44718877 External Links: ENSG00000166710

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC138811.2 chr16 18788063 18801519 - ADAR chr1 154582057 154628013 - AGPAT5 chr8 6708642 6761503 + AC011511.1 chr19 10305427 10316009 - AIFM1 chrX 130129362 130165887 - AK4 chr1 65147549 65232145 + ACLY chr17 41866917 41930542 - ABT1 chr6 26596953 26600739 + AK2 chr1 33007940 33080996 - ACADSB chr10 123008979 123058290 + ACP5 chr19 11574660 11579008 - ACP1 chr2 264140 278283 + ALDOA chr16 30064164 30070457 + AC104109.3 chr5 134167170 134226071 - ACADM chr1 75724347 75787575 + ACTB chr7 5527148 5563784 - ACAD9 chr3 128879596 128916067 + ADM chr11 10305073 10307397 + AHSA1 chr14 77457870 77469472 + AHCY chr20 34280268 34311802 - ACBD5 chr10 27195214 27242130 - ACADVL chr17 7217125 7225266 + ABI1 chr10 26746593 26861087 - ACAT2 chr6 159762045 159779112 + ADCY3 chr2 24819169 24919839 - AC003005.1 chr19 57487718 57517559 + AJUBA chr14 22971177 22982551 - ACOT1 chr14 73537143 73543796 + ALDH5A1 chr6 24494867 24537207 + ACTR3 chr2 113890063 113962596 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-142-3p chr17 58331245 58331267 - hsa-miR-1244 chr2 231713368 231713393 + hsa-miR-3654 chr7 133034860 133034878 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC007114.1 chr17 57071814 57085024 - AC007952.4 chr17 19112000 19112636 - AC010247.1 chr19 42132555 42137099 + AC010327.5 chr19 55216660 55221616 + AC026464.2 chr16 69463844 69466264 + AC074032.1 chr12 50112197 50165618 + AC091965.4 chr5 8444949 8445535 - AC093157.1 chr1 101025844 101090513 + AC139149.1 chr17 81514047 81527776 + AC144548.1 chr12 110387463 110445548 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.