exRNAdisease

Entry Detail

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General Information

Database ID: exR0430115 RNA Name: BRWD1 RNA Type: mRNA Chromosome: chr21 Starnd: - Coordinate: Start Site(bp): 39184176 End Site(bp): 39321559 External Links: ENSG00000185658

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB10 chr1 229516582 229558707 - AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC026954.2 chr17 7312661 7319174 - AC068946.2 chr2 219209772 219222738 - AC104452.1 chr3 49416777 49429314 - ADCY9 chr16 3953387 4116442 - ADGRG6 chr6 142301854 142446266 + ADORA2A chr22 24417879 24442357 + ADPRHL2 chr1 36088892 36093932 + AGAP3 chr7 151085831 151144436 + AGO2 chr8 140520156 140635633 - AL136295.1 chr14 24189157 24213473 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-19a-3p chr13 91350939 91350961 + hsa-miR-23b-3p chr9 95085265 95085287 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012146.1 chr17 5111468 5115004 + AC016876.2 chr17 7581964 7584086 - AC018521.1 chr17 47945424 47981736 + AC067930.1 chr8 143579636 143580670 + AD000090.1 chr19 35557956 35581954 + AL096870.2 chr14 24209646 24215987 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.