exRNAdisease

Entry Detail

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General Information

Database ID: exR0430119 RNA Name: BSG RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 571277 End Site(bp): 583493 External Links: ENSG00000172270

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC1 chr16 15949577 16143074 + ABCC5 chr3 183919934 184017939 - ABCF1 chr6 30571393 30597179 + AC005258.1 chr19 2269525 2341172 + AC010422.3 chr19 12643831 12648397 - AC011005.1 chr7 129126518 129130793 + AC012531.3 chr12 53985845 54034888 + AC058822.1 chr4 53377839 54295272 + AC104109.3 chr5 134167170 134226071 - AC245033.1 chr15 82536788 82573194 - ACBD4 chr17 45132600 45144181 + ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ACVR2B chr3 38453890 38493142 + ADH5 chr4 99070978 99088801 - ADPRHL2 chr1 36088892 36093932 + ADRA1D chr20 4220630 4249287 - AGAP3 chr7 151085831 151144436 + AGAP4 chr10 45825594 45853875 - AGFG1 chr2 227472152 227561214 + AGPAT4 chr6 161129967 161274061 - AHCY chr20 34280268 34311802 - AHNAK chr11 62433542 62556235 - AKAP17A chrX 1591604 1602520 + AKT1 chr14 104769349 104795751 - AL133352.1 chr10 100505628 100529881 - AL139353.1 chr14 31334312 31457441 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-664b-5p chrX 154768596 154768619 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007161.3 chr7 7640752 8004053 + AC007952.4 chr17 19112000 19112636 - AC012531.2 chr12 54017110 54035361 + AC124068.2 chr15 89335053 89336161 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL035458.2 chr20 34234840 34281173 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.