exRNAdisease

Entry Detail

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General Information

Database ID: exR0430816 RNA Name: CCT5 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 10249929 End Site(bp): 10266389 External Links: ENSG00000150753

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010422.5 chr19 12664828 12669397 - AC010463.1 chr19 17267418 17282966 + AC091167.2 chr15 90249556 90272208 + AC137834.1 chr12 57249609 57296484 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAM17 chr2 9488486 9556732 - ADD2 chr2 70607618 70768225 - ADGRL2 chr1 81306160 81992436 + ADH5 chr4 99070978 99088801 - ADNP chr20 50888916 50931437 - AGPAT1 chr6 32168212 32178096 - AGRN chr1 1020120 1056118 + AHCYL1 chr1 109984765 110023742 + AIF1L chr9 131096476 131123152 + AKIRIN1 chr1 38991276 39006059 + AKT1S1 chr19 49869033 49878459 - AL121594.1 chr14 35122549 35317474 + AL133352.1 chr10 100505628 100529881 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302c-3p chr4 112648366 112648388 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008649.1 chr19 38596346 38601694 + AC009831.1 chr18 31942575 31944156 + AC069281.2 chr7 100572232 100578700 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.