exRNAdisease

Entry Detail

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General Information

Database ID: exR0431170 RNA Name: CFL1 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 65823022 End Site(bp): 65862026 External Links: ENSG00000172757

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKAP8 chr19 15353385 15379798 - AC004922.1 chr7 99325879 99394653 + AL133352.1 chr10 100505628 100529881 - AHCYL2 chr7 129225023 129430211 + AC010422.6 chr19 12525720 12580975 - AHCY chr20 34280268 34311802 - AFDN chr6 167826922 167972023 + ALDH6A1 chr14 74056847 74084492 - AC073082.1 chr2 48632291 48755724 - AEN chr15 88621337 88632281 + ACTG1 chr17 81509971 81523847 - AFG3L2 chr18 12328944 12377227 - AASDHPPT chr11 106075501 106098699 + AHNAK2 chr14 104937244 104978374 - AKT2 chr19 40230317 40285536 - ACTB chr7 5527148 5563784 - ADPRH chr3 119579268 119589945 + AC092647.5 chr7 55887277 55955239 + ACBD3 chr1 226144679 226186741 - ABCB7 chrX 75051048 75156732 - ACTA1 chr1 229431245 229434098 - ABI1 chr10 26746593 26861087 - AC011462.1 chr19 41350853 41425001 + AKR1C1 chr10 4963253 4983283 + ACAT2 chr6 159762045 159779112 + AC010463.1 chr19 17267418 17282966 + AC010422.3 chr19 12643831 12648397 - AKAP12 chr6 151239967 151358559 + AKR1B1 chr7 134442356 134459284 - AC009133.6 chr16 29812261 29820092 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-155-5p chr21 25573983 25574006 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC004687.1 chr17 58330884 58332508 - AC007952.4 chr17 19112000 19112636 - AC026362.1 chr12 122975320 122982907 + AC132217.1 chr11 2129121 2129964 - AC144548.1 chr12 110387463 110445548 - ADARB2-AS1 chr10 1526637 1556984 + AFDN-DT chr6 167822103 167826812 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.