exRNAdisease

Entry Detail

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General Information

Database ID: exR0431317 RNA Name: CKB RNA Type: mRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 103519667 End Site(bp): 103522833 External Links: ENSG00000166165

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AHNAK chr11 62433542 62556235 - AL513165.2 chr9 37512547 37592469 - AC093525.2 chr16 2496032 2520218 + AC068580.4 chr11 1734821 1763954 - AL669918.1 chr6 32813767 32838822 - AC116366.3 chr5 132410832 132646079 + ACADVL chr17 7217125 7225266 + AHCY chr20 34280268 34311802 - AL136295.1 chr14 24189157 24213473 - AHSA1 chr14 77457870 77469472 + AATF chr17 36948954 37056871 + AC069503.2 chr12 121888809 121921470 + ADD1 chr4 2843857 2930076 + ALDH9A1 chr1 165662216 165698863 - AKAP8L chr19 15380050 15419141 - AFF1 chr4 86935002 87141054 + AL121845.3 chr20 63708864 63739103 + ACACA chr17 37084992 37406836 - AGO2 chr8 140520156 140635633 - ALDOA chr16 30064164 30070457 + ACOT7 chr1 6264269 6394391 - AC010132.3 chr7 42909273 42932174 - AC011448.1 chr19 19516227 19536076 + AIF1L chr9 131096476 131123152 + AKR1B1 chr7 134442356 134459284 - AGAP1 chr2 235494043 236131800 + AL360181.3 chr10 133380017 133420271 + ACTB chr7 5527148 5563784 - AC010323.1 chr19 8308283 8321379 - ACTG1 chr17 81509971 81523847 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010729.1 chr2 5726253 5730355 + AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC026471.1 chr16 31456711 31459736 - AC093827.4 chr4 86924630 86936202 - AC108134.2 chr16 3156736 3157483 - AL049795.2 chr1 32170733 32176568 + AL133367.1 chr14 103525010 103529072 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.