exRNAdisease

Entry Detail

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General Information

Database ID: exR0431447 RNA Name: CNBP RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 129169484 End Site(bp): 129183922 External Links: ENSG00000169714

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD17C chr15 80679684 80755621 + ABR chr17 1003518 1229738 - AC023055.1 chr12 55757275 55827546 - AC040162.1 chr16 67929614 67936017 - AC048338.1 chr12 122207779 122266423 - AC104472.3 chr3 155763043 155854442 - AC116366.3 chr5 132410832 132646079 + ACTA2 chr10 88935074 88991339 - ACTB chr7 5527148 5563784 - ACTN4 chr19 38647649 38731589 + ADIPOR1 chr1 202940826 202958572 - ADIPOR2 chr12 1688574 1788674 + ADNP2 chr18 80109262 80147523 + ADO chr10 62804720 62808479 + ADSL chr22 40346500 40390463 + AEN chr15 88621337 88632281 + AFAP1L1 chr5 149271859 149343637 + AFF1 chr4 86935002 87141054 + AGAP4 chr10 45825594 45853875 - AGPAT3 chr21 43865223 43987592 + AICDA chr12 8602170 8612867 - AJUBA chr14 22971177 22982551 - AL022238.4 chr22 40346529 40410054 + AL035078.4 chr11 31812391 32104665 + AL603832.3 chr1 112702614 112711433 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-345-5p chr14 100307876 100307897 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005062.1 chr7 19918981 20140453 - AC009084.1 chr16 66942712 66963256 + AC009133.5 chr16 29808679 29812227 + AC087190.3 chr16 9104848 9113181 + AC099329.1 chr3 42785087 42852428 - AC104109.4 chr5 134205614 134371044 - AL096870.2 chr14 24209646 24215987 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.