exRNAdisease

Entry Detail

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General Information

Database ID: exR0432627 RNA Name: EEF1A1 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 73515750 End Site(bp): 73523797 External Links: ENSG00000156508

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADNP chr20 50888916 50931437 - AIF1L chr9 131096476 131123152 + AC008982.1 chr19 38817471 38840178 - ADRM1 chr20 62302093 62308862 + ALDH16A1 chr19 49453225 49471050 + AGO2 chr8 140520156 140635633 - ALDOA chr16 30064164 30070457 + ACIN1 chr14 23058564 23095614 - ACAT1 chr11 108116695 108147603 + ADA chr20 44619522 44652233 - AC073508.2 chr17 40627356 40665141 - ABCF1 chr6 30571393 30597179 + AKT2 chr19 40230317 40285536 - ADORA2A chr22 24417879 24442357 + ACTB chr7 5527148 5563784 - ABRACL chr6 139028745 139043302 + AIDA chr1 222668013 222713210 - ACTR1A chr10 102461881 102502712 - ALDH9A1 chr1 165662216 165698863 - ACTG1 chr17 81509971 81523847 - AL035078.4 chr11 31812391 32104665 + AC015813.2 chr17 57989038 58007246 - ACACA chr17 37084992 37406836 - AC018523.2 chr11 14493783 14520344 - ABHD2 chr15 89087459 89202355 + ACAP1 chr17 7336529 7351477 + AGL chr1 99850361 99924023 + AL121758.1 chr20 646626 675800 - ACAA2 chr18 49782164 49813953 - AC008763.3 chr19 7678501 7682854 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-21-5p chr17 59841273 59841294 + hsa-miR-142-3p chr17 58331245 58331267 - hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-6797-3p chr19 41869675 41869696 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC004816.1 chr14 70809841 70815994 + AC012236.1 chr15 31221999 31230838 - AC015813.1 chr17 57989039 57994850 - AC016876.2 chr17 7581964 7584086 - AC019205.1 chr6 73263212 73301789 + AC020663.1 chr16 4730115 4752565 - AC023509.1 chr12 53441741 53467528 + AC063949.2 chr12 92421531 92483680 + AC092490.1 chr12 8788253 8795789 + AC104461.1 chr1 200333193 200478669 + AC132217.1 chr11 2129121 2129964 - AC139149.1 chr17 81514047 81527776 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL031058.1 chr6 7540451 7541338 - AL035458.2 chr20 34234840 34281173 - AL080317.2 chr6 111309203 111313517 + AL121985.1 chr1 160670778 160699761 + AL132780.1 chr14 22929607 22956374 + AL137026.2 chr10 44259602 44261813 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.