exRNAdisease

Entry Detail

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General Information

Database ID: exR0432634 RNA Name: EEF1D RNA Type: mRNA Chromosome: chr8 Starnd: - Coordinate: Start Site(bp): 143579697 End Site(bp): 143599541 External Links: ENSG00000104529

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - ABCA2 chr9 137007234 137028922 - ABCC5 chr3 183919934 184017939 - ABHD10 chr3 111979010 111993368 + AC012184.2 chr16 70299194 70372582 + AC074143.1 chr16 67163385 67165815 + AC090004.1 chr3 14135217 14148252 + AC092143.1 chr16 89919165 89936092 + AC092647.5 chr7 55887277 55955239 + AC093525.2 chr16 2496032 2520218 + AC244197.3 chrX 149477104 149540926 - AC245033.1 chr15 82536788 82573194 - ACLY chr17 41866917 41930542 - ACTA1 chr1 229431245 229434098 - ACTB chr7 5527148 5563784 - ACTC1 chr15 34790230 34795549 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ADGRE5 chr19 14380501 14408725 + AFMID chr17 78187317 78207701 + AHCYL2 chr7 129225023 129430211 + AL713999.1 chr1 155169409 155187272 - ALDH9A1 chr1 165662216 165698863 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4517 chr16 28958587 28958611 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC067930.1 chr8 143579636 143580670 + AC069281.2 chr7 100572232 100578700 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL132780.1 chr14 22929607 22956374 + AL133166.1 chr14 29210986 29392048 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.