exRNAdisease

Entry Detail

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General Information

Database ID: exR0432723 RNA Name: EIF3E RNA Type: mRNA Chromosome: chr8 Starnd: - Coordinate: Start Site(bp): 108201216 End Site(bp): 108435333 External Links: ENSG00000104408

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABLIM1 chr10 114431113 114768061 - AC008764.4 chr19 16577642 16660115 - AC009133.6 chr16 29812261 29820092 + AC012184.2 chr16 70299194 70372582 + AC048338.1 chr12 122207779 122266423 - AC079447.1 chr2 99141485 99322741 + AC092587.1 chr2 99154998 99195298 + AC104452.1 chr3 49416777 49429314 - AC120057.2 chr17 7240427 7244635 - ACTB chr7 5527148 5563784 - ADK chr10 74151202 74709963 + AHCY chr20 34280268 34311802 - AL136454.1 chr1 192716132 192716653 + ALCAM chr3 105366909 105576900 + ALDH1B1 chr9 38392702 38398661 + ALDH5A1 chr6 24494867 24537207 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-93-5p chr7 100093815 100093837 - hsa-miR-4284 chr7 73711327 73711344 + hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010618.3 chr19 17488990 17511889 - AC021078.1 chr5 149494314 149504670 - AC124312.5 chr15 25091786 25107469 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.