exRNAdisease

Entry Detail

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General Information

Database ID: exR0432735 RNA Name: EIF4B RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 53006158 End Site(bp): 53042209 External Links: ENSG00000063046

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABLIM1 chr10 114431113 114768061 - AC008763.3 chr19 7678501 7682854 + AC010422.3 chr19 12643831 12648397 - AC011462.1 chr19 41350853 41425001 + AC058822.1 chr4 53377839 54295272 + AC073508.2 chr17 40627356 40665141 - AC093525.1 chr16 2513965 2527955 + AC124312.1 chr15 24955034 25000276 + AC245033.1 chr15 82536788 82573194 - ACADVL chr17 7217125 7225266 + ACOT8 chr20 45841721 45857405 - ACSF2 chr17 50426158 50474845 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACVR1 chr2 157736444 157876330 - ADAL chr15 43330657 43354555 + ADAR chr1 154582057 154628013 - ADIPOR2 chr12 1688574 1788674 + ADORA2A chr22 24417879 24442357 + AEN chr15 88621337 88632281 + AGBL5 chr2 27042364 27070622 + AHCY chr20 34280268 34311802 - AIG1 chr6 143060496 143341058 + AIMP1 chr4 106315544 106349456 + AKNA chr9 114334156 114394405 - AL121594.1 chr14 35122549 35317474 + AL139011.2 chr1 160216800 160285130 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3680-5p chr16 21506101 21506122 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC018647.2 chr7 35695214 35699413 + AC023509.1 chr12 53441741 53467528 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL118506.1 chr20 63861212 63864293 - AL121832.3 chr20 62402236 62405935 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.