exRNAdisease

Entry Detail

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General Information

Database ID: exR0432742 RNA Name: EIF4G1 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 184314495 End Site(bp): 184335358 External Links: ENSG00000114867

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB8 chr7 151028422 151047782 + ABL1 chr9 130713016 130887675 + ABL2 chr1 179099330 179229684 - AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC025165.3 chr12 57772660 57797554 + AC137834.1 chr12 57249609 57296484 - ACTB chr7 5527148 5563784 - ACTR2 chr2 65227753 65271253 + ADAMTS1 chr21 26835755 26845409 - ADGRV1 chr5 90529344 91164437 + AIDA chr1 222668013 222713210 - AK2 chr1 33007940 33080996 - AKAP12 chr6 151239967 151358559 + AKAP8L chr19 15380050 15419141 - AKIRIN2 chr6 87674860 87702233 - AKT2 chr19 40230317 40285536 - ALCAM chr3 105366909 105576900 + ALDH3A2 chr17 19648136 19685760 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6797-3p chr19 41869675 41869696 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008124.1 chr12 45718046 45727775 - AC124068.2 chr15 89335053 89336161 + AC245014.3 chr1 145281116 145281462 + AL096870.2 chr14 24209646 24215987 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.