exRNAdisease

Entry Detail

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General Information

Database ID: exR0432747 RNA Name: EIF5A RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 7306999 End Site(bp): 7312463 External Links: ENSG00000132507

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDH3A2 chr17 19648136 19685760 + AC010422.3 chr19 12643831 12648397 - ABCD3 chr1 94418389 94518666 + ACO2 chr22 41469117 41528989 + AKR1A1 chr1 45550543 45570049 + ADO chr10 62804720 62808479 + ADAM23 chr2 206443532 206621127 + ACTR3B chr7 152759749 152855378 + AKIRIN1 chr1 38991276 39006059 + ACTN1 chr14 68874143 68979440 - AC093525.2 chr16 2496032 2520218 + AHCY chr20 34280268 34311802 - ALDH2 chr12 111766887 111817532 + AASS chr7 122073549 122144255 - ACSL4 chrX 109624244 109733403 - AC002985.1 chr19 18907013 18934397 - AFF1 chr4 86935002 87141054 + AC068946.2 chr2 219209772 219222738 - ACTG1 chr17 81509971 81523847 - ACTA1 chr1 229431245 229434098 - AL121594.1 chr14 35122549 35317474 + ACIN1 chr14 23058564 23095614 - ABCB4 chr7 87401697 87480435 - AGGF1 chr5 77029251 77065234 + AC099811.2 chr17 42119674 42154916 - AC005258.1 chr19 2269525 2341172 + AL365205.1 chr6 41780349 41790141 + ADAR chr1 154582057 154628013 - AL928654.3 chr14 105487199 105492267 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-423-5p chr17 30117095 30117117 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010542.4 chr16 66549280 66551189 + AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC027097.2 chr18 57639455 57738603 + AC091564.7 chr11 6610883 6616594 - AC107068.1 chr4 47840122 47844339 - AC139887.2 chr4 760202 781859 - AL137230.2 chr14 89628921 89642671 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.