exRNAdisease

Entry Detail

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General Information

Database ID: exR0433092 RNA Name: FAM102A RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 127940582 End Site(bp): 127980989 External Links: ENSG00000167106

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACADVL chr17 7217125 7225266 + AHCY chr20 34280268 34311802 - AKAP1 chr17 57085092 57121346 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-17-5p chr13 91350618 91350640 + hsa-miR-28-5p chr3 188688794 188688815 + hsa-miR-122-5p chr18 58451088 58451109 + hsa-miR-124-3p chr8 64379210 64379231 + hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-302a-3p chr4 112648186 112648208 - hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-302c-3p chr4 112648366 112648388 - hsa-miR-20b-5p chrX 134169850 134169872 - hsa-miR-485-5p chr14 101055427 101055448 + hsa-miR-520a-5p chr19 53690895 53690915 + hsa-miR-519b-3p chr19 53695263 53695284 + hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-625-5p chr14 65471116 65471136 + hsa-miR-650 chr22 22822791 22822811 + hsa-miR-654-5p chr14 101040234 101040255 + hsa-miR-193a-5p chr17 31560016 31560037 + hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-574-5p chr4 38868056 38868078 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-708-5p chr11 79402077 79402099 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.