exRNAdisease

Entry Detail

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General Information

Database ID: exR0433285 RNA Name: FAU RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 65120630 End Site(bp): 65122177 External Links: ENSG00000149806

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA2 chr9 137007234 137028922 - ABCB9 chr12 122920951 122981649 - ABHD12 chr20 25294742 25390835 - AC007192.1 chr19 18153158 18178117 + AC008982.1 chr19 38817471 38840178 - AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC114490.2 chr1 34981533 35031741 - AC135050.2 chr16 31083439 31094956 - ACAD9 chr3 128879596 128916067 + ACAT2 chr6 159762045 159779112 + ACIN1 chr14 23058564 23095614 - ACSS1 chr20 25006230 25058980 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTN1 chr14 68874143 68979440 - ACTN4 chr19 38647649 38731589 + ADH5 chr4 99070978 99088801 - ADM chr11 10305073 10307397 + ADPRM chr17 10697594 10711558 + AGBL5 chr2 27042364 27070622 + AHCY chr20 34280268 34311802 - AL031708.1 chr16 1632259 1686715 + AL133352.1 chr10 100505628 100529881 - AL138752.2 chr9 37588413 38068687 - AL162377.3 chr13 51763951 51845159 - ALDH18A1 chr10 95605941 95656711 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4485-3p chr11 10508277 10508296 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005899.4 chr17 32328441 32329395 + AC009022.1 chr16 69976297 70065948 - AC010642.2 chr19 58309727 58327248 - AC139149.1 chr17 81514047 81527776 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.