exRNAdisease

Entry Detail

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General Information

Database ID: exR0433290 RNA Name: FBL RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 39834458 End Site(bp): 39846379 External Links: ENSG00000105202

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC8 chr11 17392498 17476879 - ABHD12 chr20 25294742 25390835 - AC006064.6 chr12 6556886 6607367 - AC008878.2 chr19 7533595 7540059 + AC010323.1 chr19 8308283 8321379 - AC010422.3 chr19 12643831 12648397 - AC092143.1 chr16 89919165 89936092 + AC116366.3 chr5 132410832 132646079 + AC138811.2 chr16 18788063 18801519 - AC245033.1 chr15 82536788 82573194 - ACADVL chr17 7217125 7225266 + ACLY chr17 41866917 41930542 - ACSL1 chr4 184755595 184826818 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACVR1B chr12 51951699 51997078 + AEN chr15 88621337 88632281 + AGAP2 chr12 57723761 57742157 - AKIRIN2 chr6 87674860 87702233 - AKR1A1 chr1 45550543 45570049 + AL160269.1 chr9 96235331 96352058 - ALDH18A1 chr10 95605941 95656711 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC067930.1 chr8 143579636 143580670 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.