exRNAdisease

Entry Detail

---



General Information

Database ID: exR0433432 RNA Name: FGFR1 RNA Type: mRNA Chromosome: chr8 Starnd: - Coordinate: Start Site(bp): 38400215 End Site(bp): 38468834 External Links: ENSG00000077782

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC4 chr13 95019835 95301475 - ABCF1 chr6 30571393 30597179 + ABHD17A chr19 1876810 1885547 - ABI2 chr2 203328239 203447728 + AC002996.1 chr12 111753890 111791418 + AC005258.1 chr19 2269525 2341172 + AC067968.1 chr19 44025354 44087318 + AC107871.1 chr15 68184032 68229718 - AC139530.2 chr17 81703371 81720539 + ACACA chr17 37084992 37406836 - ACAD10 chr12 111686056 111757107 + ACLY chr17 41866917 41930542 - ACOT7 chr1 6264269 6394391 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - AGAP1 chr2 235494043 236131800 + AGPAT5 chr8 6708642 6761503 + AKIRIN1 chr1 38991276 39006059 + AKR1E2 chr10 4786629 4848062 + AL121845.3 chr20 63708864 63739103 + AL589666.1 chr6 85557978 85615234 - ALDH4A1 chr1 18871430 18902724 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-214-3p chr1 172138816 172138837 - hsa-miR-184 chr15 79209840 79209861 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-543 chr14 101032033 101032054 + hsa-miR-1286 chr22 20249145 20249165 - hsa-miR-1294 chr5 154347153 154347174 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC022167.2 chr16 8848105 8860456 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.